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Brian Hope, 76, is among those taking part at Glenfield Hospital, in Leicester.

In normal hearts, a tiny area of tissue or cells, known as the sinus node, in the right upper chamber (atrium) generates electrical impulses that keep the heart rate regular by stimulating all four of the heart chambers.

The impulses start in the right atrium and make the left atrium contract at the same time, then travel along special pathways and down a tiny track — the His-bundle — in the centre of the heart which branches into the left and right bottom chambers (ventricles).

Lee describes herself as having "no athletic background whatsoever," and says she has struggled with her weight her entire life.

She weighed 170 pounds when she married, and continued to gain weight during both of her pregnancies, eventually reaching 200 pounds after the birth of her second child.

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